human iPSC cells to model VCP

by | Nov 7, 2019 | Weihl, Conrad

— Valosin Containing Protein (VCP) patient derived fibroblasts, reprogrammed into iPSC cells and corresponding gene corrected line. These cells can be used to model VCP associated muscle disease, ALS, and dementia.

Therapeutic Approach for Huntington’s Disease (HD)

by | Oct 22, 2019 | Kim, Albert, Yano, Hiroko

— Dr. Hiroko Yano and Dr. Albert Kim, and their research teams at the Washington University School of Medicine in St. Louis developed and extensively evaluated a novel therapeutic approach using DNMT inhibitors to treat Huntington’s Disease (HD) and other neurodegenerative disorders. Currently D…

VISIT-TS Version 2

by | Oct 22, 2019 | Black, Kevin, Gordon, Mollie, Schroeder, Miriam, Striley, Catherine, Vachon, Matthew

— This is a brief (5 minutes exposition plus just under 5 minutes of questions) video that was designed for epidemiological research in tic disorders (including Tourette syndrome). The video shows lay people the broad definition of tics, so they can more accurately answer questions about whether they…

Normothermic Extracorporal Liver Perfusion (NELP)

by | Oct 22, 2019 | Banan, Babak, Chapman Sr., William, Lin, Yiing

— Background: In the U.S., ~15,000 adults and children are medically approved for a liver transplant and ~6,000 liver transplants are performed each year. Unfortunately, 30% of donor livers are unsuitable for transplantation while 1,500 patients per year die waiting for liver a transplant. The high de…