by | Jan 8, 2025 | Dantas, Gautam, Gorushi, Olivia, Helmink, Beth, Kwak, Suryang, Prusa, Jerome, Wallace, Miranda
— Published date: 1/9/2025
Value Proposition: Genetically engineered yeast used to treat gastrointestinal tumors through the delivery of immune checkpoint inhibitor (ICI) proteins.
Technology Description
Researchers at Washington University in St. Louis have developed a genetically engineered …
by | Jan 3, 2025 | Blake, Kevin, Dantas, Gautam, Wencewicz, Timothy, Williford, Emily, Xue, Yao-Peng
— Published Date: 1/4/2025
Value Proposition: New composition of matter that combines tetracycline class compounds with destructase inhibitors to overcome resistance to tetracycline antibiotics.
Technology Description
Researchers at Washington University in St. Louis have developed an enzymatic…
by | Jan 3, 2025 | Blake, Kevin, Dantas, Gautam, DeAngelo, Caitlin, Wencewicz, Timothy, Williford, Emily
— Published Date: 1/4/2025
Value Proposition: New composition of matter that combines tetracycline class compounds with destructase inhibitors to overcome resistance to tetracycline antibiotics.
Technology Description
Researchers at Washington University in St. Louis have developed an enzymatic…
by | Nov 18, 2019 | Dantas, Gautam, Forsberg, Kevin, Gasparrini, Andrew, Park, Jooyoung, Tolia, Niraj, Vogel, Joseph, Wencewicz, Timothy
— Disease indication – Tetracycline resistant infections
Drug format – Small molecule (anhydrotetracycline (aTC) or analogs)
Drug class – Combination therapy
Research stage and Preliminary data
Target – Tetracycline destructases (Tet(X), Tet(50), etc)
Background &ndas…