Office of Technology Management/Tech Transfer

WASHU INNOVATION CATALOG

Transgenic mouse DNAJB6/F90I

by | Aug 21, 2020 | Weihl, Conrad

— Transgenic mouse strain designed and developed by Dr. Conrad Weihl with a mutation of the DNAJB6 gene at the F90I protein. This homologous with the human form of muscular dystrophy with patients having a genetic variant at the F89I protein.

human iPSC cells to model VCP

by | Nov 7, 2019 | Weihl, Conrad

— Valosin Containing Protein (VCP) patient derived fibroblasts, reprogrammed into iPSC cells and corresponding gene corrected line. These cells can be used to model VCP associated muscle disease, ALS, and dementia.

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