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Novel Software to Increase the Accuracy of Proton TherapyO'Sullivan, Joseph ; Zhao, Tianyu ; Medrano, Maria ; Chen, Xinyuan ; Williamson, Jeffrey
T-020198
— Technology Description Developed by researchers in the Williamson and O’Sullivan Labs at the Washington University in St. Louis, this technology is a novel software platform that creates more accurate proton beam targeting to tumors. The software is used during proton therapy treatment plann…
Treatment of COVID-19 Using Fluvoxamine MaleateLenze, Eric ; Reiersen, Angela
T-019712
— Value Proposition: Novel method for treating short- and long-term symptoms of COVID-19 using a selective serotonin reuptake inhibitor (SSRI) and a sigma-1 receptor (S1R) agonist. Technology Description Researchers at Washington University in St. Louis have developed a novel method for treating …
Candidate Probiotic Strains for Improving Infant Health T-020134 & T-019665Hibberd, Matthew ; Wang, Yi ; Webber, Daniel ; Chang, Hao-Wei ; Barratt, Michael ; Gordon, Jeffrey
T-020134
— Value Proposition: Human microbe strains with robust colonization efficacy and potent in vivo harvesting of beneficial metabolites involved in infant health. Technology Description Researchers from the laboratory of Dr. Jeffrey Gordon at Washington University in St. Louis have discovered str…
Treatment of Chronic Pruritus through Intranasal or Intrathecal Delivery of Ruxolitinib or Tofacitinib (JAK inhibitors)Kim, Brian
T-015992
— Value proposition: Novel approach to treat chronic itch through the intrathecal or intranasal delivery of JAK inhibitors. Technology Description Researchers at Washington University in St. Louis have developed a new method for treating chronic idiopathic pruritus (CIP) in both patients and m…
T-020639 Using Fluorescence Lifetime to Measure Neuromodulator Dynamics Over Transient and Chronic Time ScalesMa, Pingchuan ; Chen, Yao
T-020639
— Technology Description Researchers at Washington University in St. Louis have developed a novel method that uses fluorescence lifetime to simultaneously record, and measure neuromodulator change over transient and chronic time scales, promising to reveal the roles of multi-time scale neuromodulato…
Novel PET/SPECT Radiopharmaceutical for Improving Biomedical ImagingSivapackiam, Jothilingam ; Piwnica-Worms, David ; Sharma, Vijay
T-010438
— Technology Description Researchers at Washington University in St. Louis have developed a novel positron emission tomography (PET) radiopharmaceutical for myocardial perfusion imaging. Myocardial perfusion scintigraphy is widely employed in the evaluation of patients with heart disease. Several ag…
Software used to Detect Neural Oscillations in the Time-Frequency SpaceCho, Hohyun ; Brunner, Peter
T-020025
— Technology Description Researchers at Washington University in St. Louis have developed a software method that demonstrates high precision and specificity in detecting neural oscillations in time and frequency domains. Current methods to look at identifying peaks over 1/f noise within the power s…
Highly Accurate Model used to Predict Alzheimer’s Disease StatusAli, Muhammad ; Cruchaga, Carlos
T-020673
— Technology Description Researchers at Washington University in St. Louis have developed models that can very accurately predict brain amyloidosis—Alzheimer’s disease status. Alzheimer’s disease (AD) is characterized by the accumulation of Amyloid-β (Aβ42) and hyperphos…
Novel Bile Acids as Biomarkers for Early Detection of Niemann-Pick Type C DiseaseJiang, Xuntian ; Ory, Daniel
T-014292
— Technology Description Researchers at Washington University in St. Louis have developed a set of novel bile acid biomarkers to screen, diagnose, and monitor the progression of Niemann-Pick type C (NPC) disease. Current testing for this disease takes an average of three months, is invasive (a skin…
Optimizing Patient Treatment through Electrical Stimulation for Targeted Deep Brain StimulationLeuthardt, Eric ; Willie, Jon ; Adamek, Markus ; Brunner, Peter
T-020028
— Technology Description Researchers at Washington University in St. Louis have developed a deep brain stimulation approach that can identify optimal stimulation parameters intraoperatively, which significantly reduces the amount of time spent on adapting stimulation parameters, thus reducing costs,…
Measuring Spontaneous Plasticity Pulses in Patients with Brain InjuriesNewbold, Dillan ; Dosenbach, Nico
T-019480
— Technology Description Researchers at Washington University in St. Louis have developed an analysis stream to detect and measure spontaneous plasticity pulses in patients with brain injuries. In stark contrast to existing methodologies (resting-state functional MRI and resting state functional co…
Oxonol Dyes with Near Infrared Fluorescence for Improving BioimagingFuentes, Isaac ; Berezin, Mikhail ; Birman, Vladimir
T-020648
— Value proposition: Fluorescent oxonol dyes that can be used to enhance bioimaging for the treatment of cancer. Technology Description Researchers at Washington University in St. Louis have developed a new class of fluorescent oxonol dyes that exhibit absorption and emission in the near infrared…
Novel Composition Designed to Treat Nematode InfectionsMitreva, Makedonka ; Janetka, James
T-019949
— Novel Composition Designed to Treat Nematode Infections Value proposition: Small molecule treatments designed to target the adult worm to treat nematode infections in animals. Technology Description Researchers at Washington University in St. Louis have developed novel small molecule treatment…
System and method for non-invasive brain stimulation for cognitive enhancementSingh, Matthew ; Wheelock, Jacob ; Braver, Todd ; Ching, ShiNung
T-020194
— T-020194 System and method for non-invasive brain stimulation for cognitive enhancement Technology Description Researchers at Washington University in St. Louis have developed a system that enables near- real-time control of human brain activity using non-invasive transcranial electrical curr…
Endoscopic Mucosal Graft Stabilizer Used to Treat UrethroplastyMurphy, Gregory ; McGinnis, Riley ; Wong, Daniel
T-020503
— T-020503 Endoscopic Mucosal Graft Stabilizer Used to Treat Urethroplasty Technology Description Researchers at Washington University in St. Louis have developed a sheath device designed to hold a segment of mucosal graft in the correct position to be applied over a stricture repair site. The she…
Antibodies that can Identify C. Acnes InfectionsIlagan, Maxenia ; Aleem, Alexander ; McCoy IV, William
T-020481
— Value Proposition: This invention uses antibodies to detect Cutibacterium acnes (C. acnes) infections. Technology Description Researchers at Washington University in St. Louis have developed antibodies that can identify Cutibacterium acnes (C. acnes), which opportunistically causes infection rang…
New Strategy for Treatment of Neurodegenerative Diseases with AxonopathySummers, Daniel ; Mao, Xianrong ; Milbrandt, Jeffrey ; Geisler, Stefanie ; DiAntonio, Aaron
T-017543
— Value Proposition: This invention uses a novel gene therapy that blocks the axon degeneration typical of neurodegenerative diseases. Technology Description Researchers at Washington University in St. Louis have developed a new strategy for treatment of neurodegenerative diseases with axonopathy…
New Process for Diagnosing Abnormal Heart Rhythms AutomaticallyMay, Adam
T-019674
— Technology Description Researchers at Washington University in St. Louis have developed a new method for automatically differentiating accelerated heart rhythms caused by wide complex tachycardia (WCTs) into fast, or irregularly fast heart rhythms caused by ventricular tachycardia (VT) and suprave…
VLDLR-based Decoy Receptors to Prevent Alphavirus InfectionsRaju, Saravanan ; Fremont, Daved ; Adams, Lucas ; Diamond, Michael
T-020745
— VLDLR-based Decoy Receptors to Prevent Alphavirus Infections Technology Description Researchers at Washington University in St. Louis have developed very low-density lipoprotein receptor (VLDLR) soluble decoy receptors with potent inhibitory activity in vitro and in vivo. Eastern equine encephali…
Software that Generates Radiology Reports using Deep LearningRahbar, Kasra ; Kansagra, Akash
T-018976
— T-018976 Software that Generates Radiology Reports using Deep Learning Technology Description Researchers at Washington University in St. Louis have developed a computational software method designed to assist radiologists with generating and correcting patient reports more effectively. Radiolo…
