Plasmid pHLFcHis-Glycophorin A
— Plasmid comprising the signal peptide and extracellular domain of human glycophorin A fused to antibody Fc domain and a his tag. This plasmid has been used to study malaria treatments.
Publications:
— Plasmid comprising the signal peptide and extracellular domain of human glycophorin A fused to antibody Fc domain and a his tag. This plasmid has been used to study malaria treatments.
Publications:
— Technology Description
Researchers in Prof. Niraj Tolia’s laboratory have exploited structure-based vaccine design to develop immunogenic compositions and neutralizing antibodies that could protect against malaria and a range of other parasitic diseases that affect humans, livestock and comp…
— Disease indication – Tetracycline resistant infections
Drug format – Small molecule (anhydrotetracycline (aTC) or analogs)
Drug class – Combination therapy
Research stage and Preliminary data
Target – Tetracycline destructases (Tet(X), Tet(50), etc)
Background &ndas…