by | Jan 16, 2020 | Tu, Zhude "Will"
— These materials are an alpha-synuclein binding compound (standard), and the precursor for PET radiolabeling the compound. Precursor’s code name: TZ61-23; chemical name: 2-((6-methoxypyridin-3-yl)amino)quinolin-6-ol. Standard’s code name: TZ61-44; chemical name: 6-(2-fluoroexthoxy)-N-(6-metho…
by | Dec 18, 2019 | Holtzman, David
— U87 cells that express guassia luciferase under the control of the human LDLR promoter with constitutive HRP expression.
WU878: PhLDLR/guassia luciferase
WU988: pTL/guassia luciferase
by | Dec 18, 2019 | Tu, Zhude "Will"
— TZ4877 is a ligand for the sphingosine-1-phosphate (S1P) receptor 1 in the CNS, developed and radiolabeled with fluorine-18. TZ4877 is the standard (non-radioactive compound) which is used for HPLC analysis of the S1P1 PET tracer, [18F]TZ4877. TZ50153 is the radiolabeling precursor of the PET tracer…
by | Dec 12, 2019 | Hansen, Ted, Wang, Xiaoli
— mAb 4E3 was derived by immunization of β2m-deficient BALB/c mice with a keyhole limpet hemocyanin-conjugated peptide corresponding to mMR1 residues 130–153 (L A M D Y V A H I T K Q A W E A N L H E L Q Y Q). Hybridomas were produced by standard methods and screened by anti-peptide ELISA.
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by | Dec 12, 2019 | Hansen, Ted, Lybarger, Lonnie, Wang, Xiaoli
— Target: Amino acids 11-34 of mouse tapasin.
Application(s): Western Blotting
Armenian hamster mAb (5D3) was produced to peptide EDAGGGGLSKKPATLLLRH GPRGP, representing residues 11–34 on mouse Tapasin (TPN) (44). TPN mAb was found to be specific for mouse TPN, as determined in a Western blot analysis of cell lysates of .221 (human TPN-positive) cells, .220 (human TPN-n…