Armenian Hamster Anti-Mouse Tapasin Antibody, clone 5D3
— Target: Amino acids 11-34 of mouse tapasin.
Application(s): Western Blotting
— Target: Amino acids 11-34 of mouse tapasin.
Application(s): Western Blotting
— mAb 4E3 was derived by immunization of β2m-deficient BALB/c mice with a keyhole limpet hemocyanin-conjugated peptide corresponding to mMR1 residues 130–153 (L A M D Y V A H I T K Q A W E A N L H E L Q Y Q). Hybridomas were produced by standard methods and screened by anti-peptide ELISA.
…
— Disease Indications
Drug type: Biologic – engineered protein
Drug class: First in class
Technology:
A recombinant fusion protein that depletes B cells in the recipient that are specific to the donor HLA. The fusion protein offers a targeted therapy for antibody-mediated rejection in the …