— This is a mouse knockout strain for CD26, also known as DNAM-1 (DNAX accessory molecule 1). DNAM-1 is an adhesion molecule belonging to the immunoglobulin superfamily. This mouse model was used to study the role of DNAM-1 on CD8 T cell and NK cell function in vitro and in vivo.
Publication: Gilfill…
— Mouse line knockouts of IL-34. IL-34 is a growth factor for macrophages, microglia, and Langerhans cells, among others.
Publication: IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia
— The Colonna lab generated two IL-33 knockout mouse lines – a total and a conditional knockout models. IL-33 is a crucial mediator of inflammation.
Publication: IL-33/regulatory T cell axis triggers the development of a tumor-promoting immune environment in chronic inflammation
— Reporter mouse line that allows for identification of cells productive IL-33 through mCherry expression. IL-33 is a molecule involved in immune system responses to helminths, allergies, and asthma.
Publications:
— Target: Major Histocompatibility Complex, Class 1-Related Protein
Notes: Clone available is 26.5
Publication: Evidence for MR1 Antigen Presentation to Mucosal-associated Invariant T Cells
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