CD226 (DNAM1) knockout mice

— This is a mouse knockout strain for CD26, also known as DNAM-1 (DNAX accessory molecule 1). DNAM-1 is an adhesion molecule belonging to the immunoglobulin superfamily. This mouse model was used to study the role of DNAM-1 on CD8 T cell and NK cell function in vitro and in vivo.

Publication: Gilfill…

IL34 tm1b and tm1c mice

— Mouse line knockouts of IL-34. IL-34 is a growth factor for macrophages, microglia, and Langerhans cells, among others.

Publication: IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia

IL33 tm1b and tm1c

— The Colonna lab generated two IL-33 knockout mouse lines – a total and a conditional knockout models. IL-33 is a crucial mediator of inflammation.

Publication: IL-33/regulatory T cell axis triggers the development of a tumor-promoting immune environment in chronic inflammation

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