ACE2 expressing cells
— These cells are K562 cells that express ACE2 (the receptor for SARS-CoV-2) from the endogenous locus and not a transgene.
Generating pancreatic beta cells from pluripotent stem cells for diabetes cell therapy or drug development
— Technology Description:
Researchers in Prof. Jeffrey Millman’s laboratory have developed multiple techniques for enhancing the differentiation, maturation and function of glucose-responsive, insulin-producing SC-beta cells (pancreatic beta cells made from human pluripotent stem cells). Downst…
Mouse monoclonal antibodies against SARS-CoV-2 spike protein – Colonna lab
— This panel of antibodies against the SARS-CoV-2 spike protein has potential applications for research or diagnostics (e.g., sandwich ELISA to quantify or detect spikes in biological fluid).
Inflammatory bowel disease biomarkers and therapeutic target
— Plasminogen activator inhibitor-1 (PAI-1) has been identified as a specific biomarker that is significantly elevated in patients with inflammatory bowel disease (IBD) and is correlated with disease severity. It could be used to both diagnose the disease (including ulcerative colitis and colonic Croh…
Mayaro virus monoclonal antibodies and hybridomas
— Mayaro virus (MAYV) is an emerging mosquito-transmitted alphavirus. This is a panel of 18 neutralizing mAbs agains MAYV, 11 of which have activity that inhibited infection with EC50 values <10ng/ml. Earnest, J. T., Basore, K., Roy, V., Bailey, A. L., Wang, D., Alter, G., ... & Diamond, M. S.…
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