by | Jan 12, 2021 | Lodhi, Irfan, Semenkovich, Clay
— C57BL/6 ES cells were targeted with a vector (European Conditional Mouse Mutagenesis Program) carrying loxP sites flanking exon 3 of mouse Cept1. A karyotypically normal clone (of 10 correctly targeted) was injected into B6(Cg)-Tyrc-2J/J blastocysts and chimeric mice were bred with B6(Cg)-Tyrc2J/J f…
by | Jan 12, 2021 | Kumar, Sandeep, Peterson, Timothy
— These cells are K562 cells that express ACE2 (the receptor for SARS-CoV-2) from the endogenous locus and not a transgene.
by | Jan 12, 2021 | Colonna, Marco
— Mouse strain deficient in IL-34 production with defective Langerhans cells and microglia. These mice can be used to assess the role of the cytokine IL-34 in the development and maintenance of peripheral macrophage populations.
Publication: Wang, Y., Szretter, K. J., Vermi, W., Gilfillan, S., Rossin…
by | Jan 7, 2021 | Hogrebe, Nathaniel, Millman, Jeffrey, Velazco-Cruz, Leonardo, Veronese Paniagua, Daniel, Wernes, Kristina
— Technology Description:
Researchers in Prof. Jeffrey Millman’s laboratory have developed multiple techniques for enhancing the differentiation, maturation and function of glucose-responsive, insulin-producing SC-beta cells (pancreatic beta cells made from human pluripotent stem cells). Downst…
by | Sep 22, 2020 | Cella, Marina, Colonna, Marco
— This panel of antibodies against the SARS-CoV-2 spike protein has potential applications for research or diagnostics (e.g., sandwich ELISA to quantify or detect spikes in biological fluid).