by | Oct 22, 2019 | Pathak, Amit, Sarker, Bapi
— Technology Description
Researchers in Prof. Amit Pathak’s laboratory have developed a hydrogel system that utilizes an aldehyde-based compound to easily and reliably pre-functionalize polyacrylamide for conjugation of proteins, such as collagen and fibronectin, for cell culture applications.…
by | Oct 22, 2019 | Edelson, Brian, Fremont, Daved, Liu, Chang, Nelson, Christopher, Wang, Xiaoli
— Disease Indications
Drug type: Biologic – engineered protein
Drug class: First in class
Technology:
A recombinant fusion protein that depletes B cells in the recipient that are specific to the donor HLA. The fusion protein offers a targeted therapy for antibody-mediated rejection in the …
by | Oct 22, 2019 | Dowdy, Steven
— Technology Description:
Researchers at Washington University have developed a method that allows the transduction of full-length proteins by utilizing the pTAT or pTAT-HA protein expression plasmids. A protein of choice can be fused to a HIV-TAT transduction domain under the expression system. Ba…
by | Oct 22, 2019 | Chandra, Pallavi, Philips, Jennifer
— Background: Worldwide, there are over 10 million new cases of tuberculosis (TB) annually, resulting in 1.8 million deaths. This makes Mycobacterium tuberculosis (Mtb), the bacterium causing TB, the world’s leading infectious disease killer. Even for drug susceptible TB, the treatment courses a…
by | Oct 22, 2019 | Colditz, Graham, Corcoran, Heather
— Zuum is a health-risk assessment software that serves as a prognostic for various types of cancer.