by | Jan 6, 2020 | Klechevsky, Eynav, Pathak, Amit, Sarker, Bapi
— Technology Description:
A team led by Drs. Amit Pathak and Eynav Klechevsky have developed a soft alginate-gelatin matrix-based synthetic dendritic cell to rapidly expand and deliver CD8+ T cells for cancer immunotherapy. CD8+ T cells kill tumors, but current methods to expand them also activate r…
by | Oct 22, 2019 | Pathak, Amit, Sarker, Bapi
— Technology Description
Researchers in Prof. Amit Pathak’s laboratory have developed a hydrogel system that utilizes an aldehyde-based compound to easily and reliably pre-functionalize polyacrylamide for conjugation of proteins, such as collagen and fibronectin, for cell culture applications.…
by | Oct 22, 2019 | Nasrollahi, Samila, Pathak, Amit
— Technology Description
Engineers in Prof. Amit Pathak’s laboratory have developed a 3D tissue culture device with chambers of variable, tunable stiffness to mimic the multiple microenvironments cancer cells experience in vivo as they metastasize. Traditional 3D extracellular matrix (ECM) mod…