— The Bhlhe40 flox/flox mice on the C57BL/6 background originated as a KO-first promoter-driven mouse line from the Knockout Mouse Project and were purchased from the Jackson Laboratory. These initial mice contained a Bhlhe40 allele with a splice acceptor-LacZ reporter and a Neo cassette flanked by tw…
— Disease Indications
Drug type: Biologic – engineered protein
Drug class: First in class
Technology:
A recombinant fusion protein that depletes B cells in the recipient that are specific to the donor HLA. The fusion protein offers a targeted therapy for antibody-mediated rejection in the …
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Creating...
