by | Jul 31, 2018 | Liu, Chang, Pfeifer, John
— Technology Description: In collaboration with the scientists at Broad Institute, WU scientists have developed a new software with a new algorithm that enables HLA high resolution typing from exome sequencing data. It will provide a significantly better tool to guide the bone marrow transplantation a…
by | Mar 10, 2018 | Colditz, Graham
— One important aspect for individuals to maintain health and prevent disease is through an educational understanding of making healthy choices while avoiding unhealthy choices. Clinicians at Washington University in St. Louis have created an evidence-based guide to disease prevention and healthy liv…
by | Mar 10, 2018 | Corbo, Joseph, Enright, Jennifer, Toomey, Matthew
— Optogenetics is one of the most important technological breakthroughs in neuroscience during the past decade, and holds tremendous promise for dissecting the mechanisms of neurologic disease and for treating a range of disorders. Optogenetic actuators are ion channels or pumps that can be regulated …
by | Mar 10, 2018 | Jeffe, Donna, Lieu, Judith, Umansky, Amy
— Approximately 5,000 infants are born with moderate, severe, or profound bilateral sensorineural hearing loss (HL) each year in the U.S. and many more have mild, unilateral, or progressive HL that will be identified in childhood. However, the degree of HL alone cannot predict a child’s language…
by | Mar 10, 2018 | Becker, Matthew, Fang, Huafeng, Pan, Dipanjan, Rossin, Raffaella, Sun, Xiankai, Taylor, John-Stephen, Turner, Jeffrey, Welch, Michael, Wooley, Karen
— This invention features cell permeable nano conjugates of shell-cross-linked knedel (SCK) and peptide nucleic acids (PNA) with mRNA targeting sequences for early diagnosis and therapy of cancers.