by | Dec 1, 2019 | Caparon, Michael, Flores-Mireles, Ana, Hultgren, Scott, Pinkner, Jerome
— Technology Description
Researchers at Washington University in St. Louis have developed a vaccine strategy to prevent catheter-associated urinary tract infections (CAUTIs). CAUTIs are the most common cause of hospital-acquired infections. Many of these are caused by Enterococcus bacteria. CAUTIs a…
by | Nov 13, 2019 | Bruchas, Michael, Moron-Concepcion, Jose
— This capsid expresses a dmoninant negative non-functional form of the SK2 channel present in neurons. This allows us to directly measure the effects of SK2 in hippocampal neurons.
by | Oct 22, 2019 | Pathak, Amit, Sarker, Bapi
— Technology Description
Researchers in Prof. Amit Pathak’s laboratory have developed a hydrogel system that utilizes an aldehyde-based compound to easily and reliably pre-functionalize polyacrylamide for conjugation of proteins, such as collagen and fibronectin, for cell culture applications.…
by | Oct 22, 2019 | Edelson, Brian, Fremont, Daved, Liu, Chang, Nelson, Christopher, Wang, Xiaoli
— Disease Indications
Drug type: Biologic – engineered protein
Drug class: First in class
Technology:
A recombinant fusion protein that depletes B cells in the recipient that are specific to the donor HLA. The fusion protein offers a targeted therapy for antibody-mediated rejection in the …
by | Oct 22, 2019 | Dowdy, Steven
— Technology Description:
Researchers at Washington University have developed a method that allows the transduction of full-length proteins by utilizing the pTAT or pTAT-HA protein expression plasmids. A protein of choice can be fused to a HIV-TAT transduction domain under the expression system. Ba…