— These induced pluripotent stem cell reporter cell lines were generated by introducing the following fluorescent reporters at the indicated loci:
BJFF6 cells were modified with CRISPR/Cas9 to generate these cell lines.
— Lyz2Cre;Talin-1fl/fl mouse strain
Inventors crossed Talin-1fl/fl mice (received from Oklahoma Medical Research Foundation) with Lyz2Cre mice (available at the Jackson Laboratory) to generate Lyz2Cre;Talin-1fl/fl mice.
— This is a trangenic mouse with the floxed Stat1 gene. This mouse can be breed with whole body or tissue specific Cre lines to knockout out STAT1 – which is a transcription factor that is essential for the interferon signaling pathway.
Publication: Respiratory Enterovirus (Like Parainfluenza Virus)…
— This expression plasmid can be used to identify inhibitors for Keap1 – a pathway that is invoIved in oxidative stress response and implicated in Marburg virus infection.
Publication: Dimerization controls Marburg virus VP24-dependent modulation of host antioxidative stress responses
— Plasmids for luciferase expression in Cryptosporidium
The plasmids listed below are for targeting insertion into the TK and UPRT loci in Cryptosporidium parvum. To generate the plasmids, the inventors modified a previously described nanoluciferase (Nluc) reporter fused to neomycin resistance (NeoR)…
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