— To generate a panel of antibodies against ZIKV, we serially infected Irf3/ mice 30 days apart with ZIKV MR-766 (Uganda, 1947) and ZIKV H/PF/2013 (French Polynesia, 2013). Irf3/ mice were used instead of wild-type (WT) mice, because ZIKV strains are deficient in evading type I interferon-mediated imm…
— Antibodies against Western Equine Encephalitis Virus (WEEV)
Inventors demonstrated the antibodies reactivity with WEEV-infected cells or with WEEV proteins. These antibodies can be used for diagnostic and potentially therapeutic purposes.
— Notes: Batf3-/- knockout mouse with a 129SvEv background.
— Target: Dengue Virus
Notes: PrM-12 and -22
— Primary Inventor: Michael S. Diamond, MD
Target: Venezuelan Equine Encephalitis Virus
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