by | May 13, 2025 | DeSelm, Carl, Diwan, Abhinav, Lee, Jin-Moo
— Published Date: 5/14/2025
Value proposition: Self-sustaining chimeric macrophages as a novel approach to target amyloid plaques resulting in improved efficacy and survival in patients.
Technology Description
Researchers from Washington University in St. Louis have engineered macrophages to expre…
by | May 12, 2025 | Singh, Nathan
— Published Date: 12/24/2024
Value proposition: An advanced CAR-T cell therapy engineered to reduce T cell exhaustion, enhancing durability and effectiveness in cancer treatment by overcoming one of the leading causes of long-term treatment failure.
Technology Description
Researchers at Washington…
by | May 9, 2025 | Cao, Siyan, Deepak, Parakkal
— Published Date: 5/10/2025
Value Proposition: Diagnostic method that uses the patient’s PBMCs acquired before or immediately after the onset of IL-23 therapy to determine the presence of signatures indicative of long-term IL-23 response.
Technology Description
Researchers at Washington Univ…
by | Dec 30, 2024 | Choi, Kyunghee, Kabir, Ashraf Ul, Krchma, Karen
— Published Date: 12/31/2024
Value Proposition: Novel immune-gene therapy for treatment of cancer.
Technology Description
Solid neoplasms are difficult to treat using immune checkpoint inhibitors in part because of the immunosuppressive nature of the tumor microenvironment. Researchers at Washin…
by | Dec 20, 2024 | Hahm, Hannah, Liu, Fang, Samineni, Vijay, Yang, Lite
— Published Date: 12/21/24
Value proposition: Powerful, high throughput platform that allows for the multiplex tracing of projection neurons to obtain a snapshot of activity-dependent recruitment of distinct projection neurons and their molecular features.
Technology Description
Researchers at…