by | Dec 30, 2024 | Choi, Kyunghee, Kabir, Ashraf Ul, Krchma, Karen
— Published Date: 12/31/2024
Value Proposition: Novel immune-gene therapy for treatment of cancer.
Technology Description
Solid neoplasms are difficult to treat using immune checkpoint inhibitors in part because of the immunosuppressive nature of the tumor microenvironment. Researchers at Washin…
by | Dec 23, 2024 | Singh, Nathan
— Published Date: 12/24/2024
Value proposition: Improved method using edited CAR-Ts to reduce T cell exhaustion and enhance cancer treatments.
Technology Description
High tumor burden and repeated antigen stimulation are often associated with the lack of durable remission from CAR-T therapy. Res…
by | Dec 20, 2024 | Hahm, Hannah, Liu, Fang, Samineni, Vijay, Yang, Lite
— Published Date: 12/21/24
Value proposition: Powerful, high throughput platform that allows for the multiplex tracing of projection neurons to obtain a snapshot of activity-dependent recruitment of distinct projection neurons and their molecular features.
Technology Description
Researchers at…
by | Dec 20, 2024 | Cavalli, Valeria, Feng, Rui
— Published Date: 12/21/24
Value proposition: A class of small molecule inhibitors of the endothelin B receptor has been shown to significantly enhance peripheral nerve regeneration.
Technology Description
Current treatments for peripheral nerve injury are limited to symptom relief, physical ther…
by | Feb 21, 2024 | Luff, Stephanie, Sturgeon, Christopher
— T-018886 — Scalable Generation of Hematopoietic Progenitors from Human Pluripotent Stem Cells
Technology Description
In vitro generation of CD34+ hematopoietic progenitor cells (HPC) that faithfully recapitulate in vivo behavior is an area of ongoing research. A key characteristic of CD34+ …