by | Feb 21, 2024 | Luff, Stephanie, Sturgeon, Christopher
— T-018886 — Scalable Generation of Hematopoietic Progenitors from Human Pluripotent Stem Cells
Technology Description
In vitro generation of CD34+ hematopoietic progenitor cells (HPC) that faithfully recapitulate in vivo behavior is an area of ongoing research. A key characteristic of CD34+ …
by | Jan 19, 2024 | Lomonosova, Elena, Mullen, Mary, Verma, Priyanka, Zhao, Peinan
— T-020659 — Functional Biomarkers of Platinum Chemotherapy and PARP Inhibitor Response
Technology Description
Most patients diagnosed with high-grade serous ovarian cancer (HGSOC) undergo first-line platinum therapy and PARP inhibitor maintenance therapy. However, the degree to which HGSOC p…
by | Jan 5, 2024 | Choi, Kyunghee, Kabir, Ashraf Ul, Krchma, Karen
— T-020458 — Zbtb46, a novel target for cancer therapy
Technology Description
Solid neoplasms are difficult to treat using immune checkpoint inhibitors in part because of the immunosuppressive nature of the tumor microenvironment. Researchers at Washington University School of Medicine, led b…
by | Jul 10, 2023 | Hatoum, Alexander
— Technology Description
Researchers at Washington University in St. Louis, led by Dr. Alexander Hatoum, have developed a computational model for improving the diagnosis and treatment of drug addiction. Using genome-wide association study (GWAS) of over 1 million subjects, Dr. Hatoum’s group d…
by | Jul 21, 2022 | Cohen, Barak, Zhao, Siqi
— Technology Description
Researchers in Barak Cohen’s lab at Washington University have developed a method for single cell massively parallel reporter assay (scMPRA) to preserve cell type-specific information. This technology is scalable and sequencing platform agnostic.
Massively parallel…