— Published Date: 5/14/2025
Value proposition: Self-sustaining chimeric macrophages as a novel approach to target amyloid plaques resulting in improved efficacy and survival in patients.
Technology Description
Researchers from Washington University in St. Louis have engineered macrophages to expre…
— Materials that have been used to study transcription factor EB (TFEB), a lysosomal biogenesis factor:
— Adenoviruses were generated using the Invitrogen Virapower system, which uses Clonase mediated recombination. They were generated in HEK293A cells and titered per the manufacturer’s instructions.
Publications: Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death; Impaired …
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Creating...
