by | Jan 25, 2022 | Bloom, Adam, DiAntonio, Aaron, Mao, Xianrong, Milbrandt, Jeffrey
— Technology Description
Researchers at Washington University, led by Jeffrey Milbrandt, have developed a companion diagnostic for SARM1 inhibitors that detects pathogenic variants of the SARM1 gene. Patients with one of several identified variants of SARM1 would respond well to SARM1 inhibitor thera…
by | Apr 8, 2020 | DiAntonio, Aaron, Milbrandt, Jeffrey
— Crispr developed SARM1 Knockout Rat
by | Mar 10, 2018 | DiAntonio, Aaron, Milbrandt, Jeffrey, Miller, Bradley, Press, Craig
— Background: Axonal degeneration is a feature commonly associated with many neuropathological conditions including response to injury, exposure to neurotoxins, hereditary neuropathies, glaucoma, and neurodegenerative diseases. The degenerative process is active when neuronal insults trigger a self-de…
by | Mar 10, 2018 | DiAntonio, Aaron, Milbrandt, Jeffrey, Miller, Bradley, Press, Craig
— Background: Axonal degeneration is a feature commonly associated with many neuropathological conditions including response to injury, exposure to neurotoxins, hereditary neuropathies, glaucoma, and neurodegenerative diseases. The degenerative process is active when neuronal insults trigger a self-de…