by | May 15, 2024 | DiAntonio, Aaron, Geisler, Stefanie, Mao, Xianrong, Milbrandt, Jeffrey, Summers, Daniel
— Value Proposition: This invention uses a novel gene therapy that blocks the axon degeneration typical of neurodegenerative diseases.
Technology Description
Researchers at Washington University in St. Louis have developed a new strategy for treatment of neurodegenerative diseases with axonopathy…
by | Nov 16, 2020 | Buchser, William, Lalli, Matthew, Milbrandt, Jeffrey, Mitra, Robi
— Technology Description
A team of Washington University researchers has developed a low-cost molecular diagnostics kit and reader that could provide rapid, widespread screening and surveillance for SARS-CoV-2 and other infections. This technology utilizes a reverse-transcription loop-mediated isot…
by | Apr 8, 2020 | DiAntonio, Aaron, Milbrandt, Jeffrey
— Crispr developed SARM1 Knockout Rat
by | Apr 7, 2020 | Jain, Sanjay, Milbrandt, Jeffrey
— Using the Cre-deletor strain Hoxb7-Cre, Washington University researchers developed transgenic mice with loxP sites flanking the gene for the glial cell line-derived neurotrophic factor (GDNF) family receptor α1 (GFRα1), which is involved in kidney tissue development. These mice were the…
by | Mar 10, 2018 | DiAntonio, Aaron, Milbrandt, Jeffrey, Miller, Bradley, Press, Craig
— Background: Axonal degeneration is a feature commonly associated with many neuropathological conditions including response to injury, exposure to neurotoxins, hereditary neuropathies, glaucoma, and neurodegenerative diseases. The degenerative process is active when neuronal insults trigger a self-de…