by | Nov 14, 2019 | Colonna, Marco
— Target: Cluster of Differentiation 96 protein, a.k.a. T Cell-Activated Increased Late Expression protein.
Notes: Clone name is MX92.39.
mAbs against CD96 (clone NK92.39, mouse IgG1) was obtained by immunizing mice with NK92 cells. This antibody can be used to study how NK cells recognize tumors.
Publication: Cutting Edge: CD96 (Tactile) Promotes NK Cell-Target Cell Adhesion by Interacting with the Poliovirus Receptor (CD155)
by | Nov 13, 2019 | Austin, Stephen, Diamond, Michael, VanBlargan, Laura
— Antibodies against Western Equine Encephalitis Virus (WEEV)
Inventors demonstrated the antibodies reactivity with WEEV-infected cells or with WEEV proteins. These antibodies can be used for diagnostic and potentially therapeutic purposes.
by | Nov 13, 2019 | Colonna, Marco
— Target: Cluster of Differentiation 172g protein, a.k.a. Signal Regulatory Protein Beta-2.
Notes: Clone name is LSB2.20.
Monoclonal antibodies were raised in a 4-to 8 week-old female Balb/c mouse by immunozation with a recombinant GST fusion protein containing the whole extracellular domain of SIRPB1. These can be used to study T-cell activation and the induction of antigen-specific cytotoxic T-lymphocyte responses by…
by | Nov 13, 2019 | Chen, Zhou-Feng
— Grp floxed mouse strain
These mice have loxP sites flanking exon 1 of the Grp gene. It was used to study the mechanism of itch and further interrogation of itch-nerve fibers in the skin under chronic pruritus.
Publication: Exploration of Sensory and Spinal Neurons Expressing GRP in Itch and Pain
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by | Nov 13, 2019 | Chen, Zhou-Feng
— Grpr floxed mouse strain
This mouse strain has loxP sites flanking exon 2 of the Grpr gene. Inventors backcrossed the mice into the C57Bl/6J background. The mouse strain was used to study contagious itch and demonstrated that GRP-GRPR signaling is necessary and sufficient for transmitting contagiou…
