Grpr floxed mouse strain
This mouse strain has loxP sites flanking exon 2 of the Grpr gene. Inventors backcrossed the mice into the C57Bl/6J background. The mouse strain was used to study contagious itch and demonstrated that GRP-GRPR signaling is necessary and sufficient for transmitting contagious itch information in the suprachiasmatic nucleus (SCN) of the hypothalamus in mice.
Publication: Molecular and neural basis of contagious itch behavior in mice
