anti-Powassan virus antibodies and hybridoma cell lines
— Murine anti-Powassan virus antibodies and hybridoma cell
Publication: An mRNA Vaccine Protects Mice against Multiple Tick-Transmitted Flavivirus Infections
Mouse embryonic fibroblasts from IRF 3/5/7 knock out animals
— Mouse fibroblasts are isolated from Irf3-/-xlrf5-/-xlrf7-/-TKO mice. Researchers generated the mouse strains from an inbred C57BL/6 background.
Associated Publication: IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling
αB-crystallin (cryAB) R120G mutant knock-in mice
— Researchers developed these knock-in mice by using homologous recombination to clone the R120G mutation into exon 3 of the αB-crystallin gene (cryab). αB-crystallin (cryAB) helps to maintain protein stability in the eye lens, which is necessary for transparency. The R120G mutation causes…
Plasmids with genetic variants of CEL
— These plasmids encode carboxyl ester lipase (CEL) with and without genetic variants that are associated with chronic pancreatitis.
To make the plasmids, the researchers used a full-length human CEL cDNA clone. The cDNA encoded for a 14-repeat VNTR, the variant present in the CEL MODY family. The Ec…
MOG.15 hybridoma
— MOG.15 is a T cell hybridoma that will be active when engaged with an antigen presenting cell that is presenting MOG35-55 peptide.
Publication: Conditional MHC Class II Expression Reveals a Limited Role for B Cell Antigen Presentation in Primary and Secondary CD4 T Cell Responses
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