by | May 22, 2024 | McGinnis, Riley, Murphy, Gregory, Wong, Daniel
— T-020503 Endoscopic Mucosal Graft Stabilizer Used to Treat Urethroplasty
Technology Description
Researchers at Washington University in St. Louis have developed a sheath device designed to hold a segment of mucosal graft in the correct position to be applied over a stricture repair site. The she…
by | Jan 30, 2024 | Paley, Michael, Yokoyama, Wayne
— T-020486 – Systems and Methods for Detection and Quantification of Axial Spondyloarthritis
Technology Description
Researchers at Washington University in St. Louis, led by Dr. Michael Paley, have developed an assay to diagnose axial spondyloarthritis (axSpA) in HLA-B*27-positive patients.…
by | Nov 8, 2023 | Eteleeb, Abdallah, Maher, Christopher, Silva-Fisher, Jessica
— Technology Description
Researchers in Dr. Jessica Silva-Fisher’s laboratory have developed antisense oligonucleotide targeting a long non-coding RNA (lncRNA), LINC00355, as a treatment for late-stage relapse (LSR) breast cancer. LINC00355 is highly expressed in LSR breast cancer patients and…
by | Jan 11, 2022 | Imoukhuede, Princess
— Technology Description
Researchers in the Imoukhuede lab at Washington University have developed a library of mutant PDGF-B proteins to develop more effective VEGF pathway inhibitors. As PDGF-B also binds to VEGF receptors, a mutant form can be used to block VEGF binding and stop tumor angiogenesi…
by | Nov 12, 2021 | Cabanski, Christopher, Fields, Ryan, Maher, Christopher, Silva-Fisher, Jessica
— Technology Description
Researchers in Prof. Christopher Maher’s research program (in conjunction with collaborator Ryan Fields) discovered that RAMS11 (RNA Associated with Metastasis 11), a novel long non-coding RNA, (i) promotes metastatic disease, (ii) confers resistance to topoisomerase i…