by | Nov 8, 2023 | Eteleeb, Abdallah, Maher, Christopher, Silva-Fisher, Jessica
— Technology Description
Researchers in Dr. Jessica Silva-Fisher’s laboratory have developed antisense oligonucleotide targeting a long non-coding RNA (lncRNA), LINC00355, as a treatment for late-stage relapse (LSR) breast cancer. LINC00355 is highly expressed in LSR breast cancer patients and…
by | Nov 12, 2021 | Cabanski, Christopher, Fields, Ryan, Maher, Christopher, Silva-Fisher, Jessica
— Technology Description
Researchers in Prof. Christopher Maher’s research program (in conjunction with collaborator Ryan Fields) discovered that RAMS11 (RNA Associated with Metastasis 11), a novel long non-coding RNA, (i) promotes metastatic disease, (ii) confers resistance to topoisomerase i…
by | Jun 9, 2020 | Chaudhuri, Aadel, Maher, Christopher, Pachynski, Russell
— Technology Description
A team of researchers at Washington University has developed “EnhanceAR-Seq”, a circulating tumor DNA (ctDNA) assay that predicts which patients are at high risk for developing resistance to androgen receptor (AR)-directed treatment for metastatic prostate cancer…