by | May 19, 2021 | Hotchkiss, Richard, Mazer, Monty, Remy, Kenneth, Turnbull, Isaiah
— Technology Description
A team of researchers, led by Richard Hotchkiss at Washington University in St. Louis, have developed a version of the ELISpot assay to determine if COVID-19 patients are in a hyper-inflammatory or immunosuppressed state. The results of this assay, which can be performed wit…
by | Apr 29, 2021 | Adams, Lucas, Diamond, Michael, Fremont, Daved, VanBlargan, Laura
— Disease indication – SARS-CoV-2 infection (COVID-19)
Drug format – Chimeric monoclonal antibody
Drug class – Best-in-class
Research stage and Preliminary data – The inventors have developed and characterized this antibody, creating a chimeric version with a human IgG backbone. T…
by | Apr 7, 2021 | Jun, Young-Shin, Singamaneni, Srikanth
— Technology Description
A team of researchers led by Young-Shin Jun have developed a polymer coating for N95 respirators that would permit fast, easy, and cheap N95 disinfection using only direct sunlight. The researchers coated the outermost fabric layer in polydopamine, which converts photon energ…
by | Nov 16, 2020 | Buchser, William, Lalli, Matthew, Milbrandt, Jeffrey, Mitra, Robi
— Technology Description
A team of Washington University researchers has developed a low-cost molecular diagnostics kit and reader that could provide rapid, widespread screening and surveillance for SARS-CoV-2 and other infections. This technology utilizes a reverse-transcription loop-mediated isot…
by | Sep 22, 2020 | Cella, Marina, Colonna, Marco
— This panel of antibodies against the SARS-CoV-2 spike protein has potential applications for research or diagnostics (e.g., sandwich ELISA to quantify or detect spikes in biological fluid).