— Published date: 1/14/2026
Value Proposition: Fusion protein that can be used to prevent and treat arthritogenic alphavirus infections.
Technology Description
Researchers at Washington University in St. Louis have identified MXRA8 (matrix remodeling associated protein 8) protein as a key recepto…
— Published date: 9/18/2025
Value Proposition: Single chain RANK ligand that can selectively inhibit pathological bone loss.
Technology Description
Researchers at Washington University in St. Louis have developed a genetically engineered mutant RANKL protein that prevents bone loss by selective…
— A number of bacterial and mammalian expression vectors for production of SARS-CoV proteins that can be used for immunization, B-cell sorting, and human serum evaluation are available.
Expression constructs produce: spike, ACE2, CD147, Surface display, SARS-1 and SARS-2 ORF7a, ORF8, and nucleocapsid…
— To generate a panel of antibodies against ZIKV, we serially infected Irf3/ mice 30 days apart with ZIKV MR-766 (Uganda, 1947) and ZIKV H/PF/2013 (French Polynesia, 2013). Irf3/ mice were used instead of wild-type (WT) mice, because ZIKV strains are deficient in evading type I interferon-mediated imm…
— Disease Indications
Drug type: Biologic – engineered protein
Drug class: First in class
Technology:
A recombinant fusion protein that depletes B cells in the recipient that are specific to the donor HLA. The fusion protein offers a targeted therapy for antibody-mediated rejection in the …
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Creating...
