IL34 tm1b and tm1c mice

— Mouse line knockouts of IL-34. IL-34 is a growth factor for macrophages, microglia, and Langerhans cells, among others.

Publication: IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia

IL33 tm1b and tm1c

— The Colonna lab generated two IL-33 knockout mouse lines – a total and a conditional knockout models. IL-33 is a crucial mediator of inflammation.

Publication: IL-33/regulatory T cell axis triggers the development of a tumor-promoting immune environment in chronic inflammation

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