— Target: C-X-C chemokine family member (CXCR3). Expressed on NK cells, activated T lymphocytes, select
endothelial and epithelial cells.
— Myl-CFP Mice
The coding sequence for the enhanced CFP was inserted downstream of ~5kb of putative regulatory sequences from the mouse myosin Type I heavy chain gene. Transgenic mice were generated by pronuclear injection using standard methods.
JAX Stock No. 06922
MyIIA-RFP Mice
A ~100kb genomic…
— Gadd7 haploinsufficient mutant CHO cell line
Inventors generated a mutant Chinese Hamster Ovary (CHO) cell line with disruption of one allele encoding Gadd7, a non-coding RNA. CHO cells were transduced with retrovirus at a low multiplicity of infection and mutants were isolated. Number of retrovira…
— Murine tumor cell lines
Murine syngeneic MCA induced tumor lines have been developed and characterized by the Schreiber Lab and provide critical models to study drugs or pathways that impact tumor growth or rejection. In particular they are used to study mechanism of action of immune checkpoint blo…
— This mouse strain has a genetic alteration in STAT3 and can be used to understand the role of STAT3 in human disease.
Publication: Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations
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