by | Sep 4, 2020 | Storch, Gregory, Wylie, Kristine, Wylie, Todd
— Technology Description
A team of researchers at Washington University designed patented primers for a sensitive, specific, real-time reverse transcriptase PCR (RT-PCR) assay to quickly detect enterovirus D68 (EV-D68).
EV-D68 is an emerging, highly contagious respiratory virus that can cause seve…
by | Sep 4, 2020 | Shao, Jieya
— VCP is an essential AAA+ ATPase that regulates proteostasis under normal and stressed cellular conditions. These monoclonal antibodies specifically recognize pSer784-VCP, which is phosphorylated during the DNA damage response and plays a crucial role in cellular survival upon genotoxic chemotherapy …
by | Aug 24, 2020 | Wambach, Jennifer, Yang, Ping
— ABCA3-GFP (ATP binding cassette transporter A3 gene cDNA fused to GFP) plasmid that lavels lamellar bodies.
Publication: Functional Characterization of ATP-Binding Cassette Transporter A3 Mutations from Infants with Respiratory Distress Syndrome
by | Aug 24, 2020 | Qi, Yunci, Van Dyke-Blodgett, Joshua, Wencewicz, Timothy, Yang, Jinping
— Clifednamide A and C are congeners of long known ikarugamycin. Ikarugamycin has anti-inflammatory, anti-ciliate, plant modulatory and other desirable bioactivities. These clifednamide compounds may also have therapeutic, industrial or agricultural value.
Publication: Qi, Y., Ding, E., & Blodget…
by | Aug 21, 2020 | Lavine, Kory
— This is a transgenic mouse line that expresses the Diphtheria toxin receptor in the myocardium of the mouse heart. Upon administration of Diphtheria toxin cardiomyocytes undergo rapid cell death and mice develop heart failure. This mouse line provides a simple a noninvasive method to model cardiac i…