Monoclonal antibodies against pSer784-VCP

— VCP is an essential AAA+ ATPase that regulates proteostasis under normal and stressed cellular conditions. These monoclonal antibodies specifically recognize pSer784-VCP, which is phosphorylated during the DNA damage response and plays a crucial role in cellular survival upon genotoxic chemotherapy …

ABCA3-GFP plasmid

— ABCA3-GFP (ATP binding cassette transporter A3 gene cDNA fused to GFP) plasmid that lavels lamellar bodies.

Publication: Functional Characterization of ATP-Binding Cassette Transporter A3 Mutations from Infants with Respiratory Distress Syndrome

Troponin T2-DTR transgenic mice

— This is a transgenic mouse line that expresses the Diphtheria toxin receptor in the myocardium of the mouse heart. Upon administration of Diphtheria toxin cardiomyocytes undergo rapid cell death and mice develop heart failure. This mouse line provides a simple a noninvasive method to model cardiac i…

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