Office of Technology Management/Tech Transfer

WASHU INNOVATION CATALOG

Monoclonal antibodies against pSer784-VCP

by | Sep 4, 2020 | Shao, Jieya

— VCP is an essential AAA+ ATPase that regulates proteostasis under normal and stressed cellular conditions. These monoclonal antibodies specifically recognize pSer784-VCP, which is phosphorylated during the DNA damage response and plays a crucial role in cellular survival upon genotoxic chemotherapy …

Biomarker to predict cancer response to chemotherapy

by | Jul 29, 2020 | Diamond, Marc, Shao, Jieya

— Technology Description

Researchers at Washington University in St. Louis have developed a prognostic biomarker that can be used to predict response to genotoxic chemotherapy for patients with basal-like/triple-negative breast cancer. Basal-like/triple-negative breast cancer is considered to be mor…

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