by | Nov 6, 2019 | Baldridge, Megan
— Ifnl2/Ifnl3 double knock-out mouse strain
This mouse strain is in the C57BL/6 background with Ifnl2, Ifnl3 genes disrupted to create a double knock-out. It was generated with assistance from the Washington University GEIC. This strain was used to study the regulation of the innate immune response t…
by | Oct 22, 2019 | Fremont, Daved, Lu, Yun Hsuan, Lubman, Olga
— Researchers in Prof. Daved Fremont’s laboratory have identified two potent, soluble proteins that could prevent damage to transplanted organs and potentially treat other autoimmune and inflammatory diseases by evading the immune response instigated by chemokines.
In organ transplants, chemoki…
by | Oct 22, 2019 | Morley, Sharon "Celeste", Todd, Elizabeth (Betsy)
— Technology Description
Researchers in Prof. S. Celeste Morley’s laboratory have developed a long-lasting prophylactic therapy that could protect pre-term and at-risk infants from pneumonia, respiratory distress and bronchopulmonary dysplasia. Neonates born prematurely are at increased risk f…
by | Oct 22, 2019 | Crimmins, Dan, Gaut, Joseph, Ladenson, Jack, Laterza, Omar, Lockwood, Christina, Modur, Vijay
— Technology Description
A team of researchers at Washington University in St. Louis have developed patented antibodies designed to identify MIOX (myo-inositol oxygenase), a renal-specific biomarker that can be detected immediately following acute kidney injury (AKI). AKI can be caused by surgery, s…
by | Oct 22, 2019 | Barrow, Melissa, Diamond, Michael, Fremont, Daved, Pal, Pankaj