Ifnl2/Ifnl3 double knock-out mouse

Tech ID: T-019187

Ifnl2/Ifnl3 double knock-out mouse strain

This mouse strain is in the C57BL/6 background with Ifnl2, Ifnl3 genes disrupted to create a double knock-out. It was generated with assistance from the Washington University GEIC. This strain was used to study the regulation of the innate immune response to mucosal viral infections.

Publication: Disruption of Type III Interferon (IFN) Genes Ifnl2 and Ifnl3 Recapitulates Loss of the Type III IFN Receptor in the Mucosal Antiviral Response

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Inventors

Contact

Hanford, Charles

hanford@wustl.edu

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