by | Feb 18, 2022 | Kreple, Collin, Miller, Timothy, Nielsen, Susan, Racette, Brad
— Technology Description
Researchers in Brad Racette and Tim Miller’s labs at Washington University have developed a therapeutic strategy for treating ALS by using statins to lower LDL. Statins were successful at prolonging both survival and time with a normal gait.
The researchers identif…
by | Jan 25, 2022 | Bloom, Adam, DiAntonio, Aaron, Mao, Xianrong, Milbrandt, Jeffrey
— Technology Description
Researchers at Washington University, led by Jeffrey Milbrandt, have developed a companion diagnostic for SARM1 inhibitors that detects pathogenic variants of the SARM1 gene. Patients with one of several identified variants of SARM1 would respond well to SARM1 inhibitor thera…
by | Mar 1, 2021 | Li, Jr-Shin, Zlotnik, Anatoly
— Technology Description:
Researchers in Prof. Jr-Shin Li’s laboratory have developed a robust, scalable, patented technology to control and entrain complex, noisy, non-linear oscillating systems such as neuronal firing and circadian rhythms. This system uses a single global, open-loop control …
by | Feb 12, 2021 | Bergonzi, Karla, Culver, Joseph, Eggebrecht, Adam, Ferradal, Silvina
— Technology Description
Researchers in Prof. Joseph Culver’s laboratory have developed a patented, compact, lightweight functional neuroimaging device for long-term bedside monitoring. This technology, based on high-density diffuse optical tomography (HD-DOT), could be used as a surrogate for …
by | Jan 25, 2021 | Jiang, Xuntian, Ory, Daniel
— Technology Description
Researchers at Washington University have developed and validated a set of bile acid biomarkers to screen, diagnose, and monitor the progression of Niemann-Pick disease type C (NPC), a genetic lysosomal storage disorder resulting from a defect in lipid transport. Previous ef…