Novel Bile Acids as Biomarkers for Early Detection of Niemann-Pick Type C Disease

by | Jun 18, 2024 | Jiang, Xuntian, Ory, Daniel

— Technology Description

Researchers at Washington University in St. Louis have developed a set of novel bile acid biomarkers to screen, diagnose, and monitor the progression of Niemann-Pick type C (NPC) disease. Current testing for this disease takes an average of three months, is invasive (a skin…

Sensitive and Accurate Mass Spec-based assay for simultaneous quantification of glycosylsphingosine and galactosylsphingosine

by | Oct 22, 2019 | Jiang, Xuntian, Ory, Daniel

— Background

Gaucher and Krabbe disease are two types of lipid (fat) storage diseases that can result in progressive damage to the nervous system and other organ systems. Together, these diseases affect about 450,000 people worldwide. In both of these diseases, there is an undesirable accumulation of…

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Novel Bile Acids as Biomarkers for Early Detection of Niemann-Pick Type C Disease

Sensitive and Accurate Mass Spec-based assay for simultaneous quantification of glycosylsphingosine and galactosylsphingosine

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