by | Mar 10, 2018 | Corbo, Joseph, Havranek, James, Mitra, Robi, Myers, Connie, Qi, Zongtai, Zhang, Chi
— Background: The function of enzymes involved in homologous recombination can be exploited in the field of genetic engineering in order to generate mutations of interest. However, this machinery is not functionally efficient in post mitotic or terminally differentiated cells. Viral gene therapy techn…
by | Mar 10, 2018 | An, Woo Jin, Wang, Lihong
— Photon tunneling has the potential to guide light to the core of a human body in vivo. Imaging, sensing, and therapy are among the applications for this technology. Light, as opposed to potentially harmful x-rays, is an ideal non-ionizing radiation for imaging and treating biological tissue, however…
by | Mar 10, 2018 | Alvarado, David, Dobbs, Matthew, Gurnett, Christina, Haller, Gabriel
— Background: A DNA point mutation is a single nucleotide base substitution, insertion, or deletion in a gene sequence. Point mutations are responsible for several diseases including cystic fibrosis, sickle-cell disease, polycystic kidney disease, microcephaly, and Crohn’s disease. The study on …
by | Mar 10, 2018 | Albring, Jorn, Murphy, Kenneth, Sandau, Michelle
— Background: Allogeneic hematopoietic stem-cell transplantation (aHSCT) from a healthy donor can cure a variety of blood cell disorders including leukemia, multiple myeloma, and some types of lymphoma. This has resulted in an increasing number of transplants, surpassing 8,000 a year in the US alone. …
by | Mar 10, 2018 | Danieley, Jonathan, LaBrash, Jason, Mutic, Sasa, Santanam, Lakshmi, Scholle, Glen
— Software management tool for clinic business manager & coordination tool. Collects information on patient flow, treatment plans, machine availability and personnel to optimize clinic operations.