by | Mar 10, 2018 | Corbo, Joseph, Enright, Jennifer, Toomey, Matthew
— Optogenetics is one of the most important technological breakthroughs in neuroscience during the past decade, and holds tremendous promise for dissecting the mechanisms of neurologic disease and for treating a range of disorders. Optogenetic actuators are ion channels or pumps that can be regulated …
by | Mar 10, 2018 | Lanza, Gregory, Pan, Dipanjan, Senpan, Angana, Wickline, Samuel
— Background: Biodegradable magnetic carriers have been increasingly utilized in biomedical and clinical research, but the larger size of ferromagnetic agents previously used leads to long circulation times and restriction to the vasculature, making these particles ideally suited for detection of spa…
by | Mar 10, 2018 | Becker, Matthew, Fang, Huafeng, Pan, Dipanjan, Rossin, Raffaella, Sun, Xiankai, Taylor, John-Stephen, Turner, Jeffrey, Welch, Michael, Wooley, Karen
— This invention features cell permeable nano conjugates of shell-cross-linked knedel (SCK) and peptide nucleic acids (PNA) with mRNA targeting sequences for early diagnosis and therapy of cancers.
by | Mar 10, 2018 | Dodd, Sherry, Garbutt, Jane, Highstein, Gabrielle, Rook, Shannon, Strunk, Robert
— Background: Many children with asthma live with frequent symptoms and activity limitations, and visits for urgent care are common. Pediatricians do not typically meet with families regularly in order to monitor asthma, identify possible problems with the management of the child’s asthma, or pr…
by | Mar 10, 2018 | Achilefu, Samuel, Berezin, Mikhail, Zhang, Zongren
— Background: Near Infrared (NIR) fluorescence can be highly useful in biological systems as it is highly sensitive and allows for detection and imaging of physiological and molecular processes in cells and living organisms. However, radiometric imaging is difficult in the NIR region of the light spec…