by | Mar 10, 2018 | Lam, Woei Chuan, Lodge, Jennifer, Upadhya, Rajendra
— Cryptococcus fungi are pathogenic fungi that, unless treated, are invariably fatal to those individuals infected, particularly to those who are immunocompromised. Recent reports indicate that Cryptococcus fungi infects 1,000,000 individuals per year and causes approximately 600,000 deaths. While ant…
by | Mar 10, 2018 | Chen, Zhou-Feng, Sun, Yan Gang
— Background: Severe itch (or pruritus) is associated with multiple diseases such as liver disease, non-Hodgkin’s lymphoma, psoriasis, and common eczema and is also a side effect of many treatments including analgesics (like morphine) and renal dialysis. Chronic pruritus is a top reason for derm…
by | Mar 10, 2018 | Kotzbauer, Paul, Mach, Robert, Tu, Zhude "Will", Yu, Lihai
— A novel series of phenothiazine-derived molecules are useful for detecting Parkinson’s disease using positron emission tomography (PET) imaging. The molecules bind with high affinity to the alpha- synuclein protein, which forms aggregates in the brain and is associated with the neurodegenerati…
by | Mar 10, 2018 | Druley, Todd, Young, Andrew
— Next Generation Sequencing (NGS) allows rapid sequencing of an individual’s entire genome or portions of the genome to identify thousands of genetic variants. Personalized genomic tests based on NGS technologies can be used to predict an individual’s risk of disease or monitor disease pr…
by | Mar 10, 2018 | Ravi, V. Nathan
— The present hydrogel technology can be used as a lens replacement material for the permanent treatment of cataracts and presbyopia as well as a vitreous substitute. This co-polymeric hydrogel system can be reversibly converted between a hydrogel in the oxidized state and a solution in the reduced st…