by | Jan 31, 2020 | McAlinden, Audrey, O'Keefe, Regis, Shen, Jie
— A team of researchers at Washington University in St. Louis has identified an epigenetic pathway and two therapeutic targets that could be used to prevent cartilage loss and counteract the mechanism underlying osteoarthritis. The inventors have seen promising results in a mouse model of arthritis us…
by | Jan 23, 2020 | Altan, Ege, Chakrabartty, Shantanu, Chandak, Rishabh, Mehta, Darshit, Raman, Baranidharan, Saha, Debajit, Singamaneni, Srikanth, Tadepalli, Sirimuvva, Traner, Michael
— Technology Description
Prof. Barani Raman and colleagues have developed a robust, insect-based, non-invasive sensing system to detect explosives or other chemicals. This “artificial nose” technology includes methods to decode neural signals from the insect’s olfactory system and …
by | Jan 21, 2020 | Liu, Hui, Rosenberg, Adam, Tu, Zhude "Will", Yue, Xuyi
— Technology Description
Researchers at Washington University in St. Louis have developed sphingosine 1-phosphate receptor 1 (S1P1)-specific PET tracers. Sphingosine 1-phosphate receptors are G-protein coupled receptors, with five subtypes denoted S1P1-5, that have key functions in immune, inflammat…
by | Jan 15, 2020 | Boyle, Walter
— Background: Vasodilatory shock, a reduction in effective blood circulation, occurs when endogenous vasoconstrictor mechanisms fail as a result of an often lethal combination of severe infections. Sepsis, as one of the causes, alone affects 1 million people resulting in more than 258,000 deaths each …
by | Jan 14, 2020 | Johnson, Tim, Leuthardt, Eric, Moran, Daniel, Reynolds, Benton, Stoev, Ivan, Wright, Neill
— Technology Description
A team of researchers at Washington University have developed ACALADE (Advanced Capability Lumbar Discectomy), a device designed to help surgeons safely access and quickly remove the back portions of herniated discs for faster, lower risk lumbar discectomy.
Currently, about…