by | Jun 11, 2021 | Shen, Hua
— Technology Description:
A team of researchers at Washington University has developed a cell-free, nano-sized extracellular vesicle (EV/exosome) system to enhance repair of soft musculoskeletal tissue. This technology leverages the natural anti-inflammatory effects of adipose-derived stem cells (ASC…
by | Mar 17, 2021 | Djuranovic, Sergej
— Technology Description
Researchers in Prof. Sergej Djuranovic’s laboratory have discovered short DNA coding motifs that can increase or decrease expression of recombinant proteins by 3-4 orders of magnitude in a variety of organisms. Together, these universal tools can provide tightly contro…
by | Jan 15, 2021 | Amatya, Parmeshwar, Carter, Alun, Cooper, Matthew, DiPersio, John
— Technology Description
A team of researchers, led by John DiPersio and Matthew Cooper at Washington University in St. Louis, have identified a small molecule kinase inhibitor capable of mitigating cytokine release syndrome following CAR-T cell therapy. PI3K inhibitors can suppress production of IL-…
by | Jan 12, 2021 | Granas, David, Roy, Basab, Stormo, Gary, White, Michael A
— This plasmid was created to test the regulatory impact of 5’ untranslated regions in yeast. It consists of EGFP under the control of the S. cerevisiae TEF2 promoter with cloning sites to modify the 5’UTR.
Publication: Roy, B., Granas, D., Bragg, F., Cher, J. A., White, M. A., & Stor…
by | Jan 12, 2021 | Granas, David, Roy, Basab, Stormo, Gary, White, Michael A
— Three yeast plasmids that express yeast genes tagged with the fluorescent mCherry protein under the control of the GAL promoter. The genes were modified to be cre-less to so the plasmids could be used to study autoregulation in yeast.
pMBJ1
pMBJ1-RPL1B-cl
pMBJ1-RPS22-cl
Publication: Roy, B., Gr…