— The Colonna lab generated two IL-33 knockout mouse lines – a total and a conditional knockout models. IL-33 is a crucial mediator of inflammation.
Publication: IL-33/regulatory T cell axis triggers the development of a tumor-promoting immune environment in chronic inflammation
— Reporter mouse line that allows for identification of cells productive IL-33 through mCherry expression. IL-33 is a molecule involved in immune system responses to helminths, allergies, and asthma.
Publications:
— Technology Description
An interdisciplinary team of researchers at Washington University have developed a universal system designed to extend the lifetime of implantable and wearable biosensors by protecting detection antibodies from harsh conditions and enabling a refreshing process to release bo…
— Six recombinant human monoclonal antibodies that are directed against the conserved stalk region of influenza virus HA. This stalk region is currently being assessed as a potential candidate as a universal influenza vaccine. These antibodies can be used as diagnostics and also as validation tools fo…
— New combinations of labeled membrane proteins and G-protein subunits. These include twocolor HRas and single color CD86 controls as well as labels beta and gamma subunits of the heterotrimeric G-protein complex. All of these have been built using plasmids from Addgene.
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