by | Mar 10, 2022 | Kremer, Jeff, Lange, Sara, Van Tine, Brian
— Background: Synovial sarcoma is a rare soft tissue sarcoma that most commonly affects young adults. Like many other cancers, there are currently no targeted chemotherapies for synovial sarcoma. Current treatment often consists of a combination of surgery, radiation therapy, and chemotherapy. The met…
by | Mar 10, 2022 | Kremer, Jeff, Lange, Sara, Van Tine, Brian
— Background: Synovial sarcoma is a rare soft tissue sarcoma that most commonly affects young adults. Like many other cancers, there are currently no targeted chemotherapies for synovial sarcoma. Current treatment often consists of a combination of surgery, radiation therapy, and chemotherapy. The met…
by | Sep 29, 2021 | Ellebedy, Ali
— Disease indication – SARS-CoV-2 infection (COVID-19)
Drug format
Drug class – Best-in-class
Research stage and Preliminary data – The inventors have developed and characterized these antibodies, creating a chimeric version with a human IgG backbone for SARS2-38. The antibodies have …
by | May 19, 2021 | Colonna, Marco
— Disease indication – In combination with anti-PD-1 therapy for cancer. Anti-PD-1 therapy is currently approved for:
Drug format – Monoclonal antibody
Drug class – First-in-class
Target – TREM2
Research stage and preliminary data – The inventors performed initia…
by | May 19, 2021 | Hotchkiss, Richard, Mazer, Monty, Remy, Kenneth, Turnbull, Isaiah
— Technology Description
A team of researchers, led by Richard Hotchkiss at Washington University in St. Louis, have developed a version of the ELISpot assay to determine if COVID-19 patients are in a hyper-inflammatory or immunosuppressed state. The results of this assay, which can be performed wit…