Murine Hybridoma producing IgG1 Monoclonal Antibody to Human CD155
— Target: Cluster of Differentiation 155 protein, a.k.a. Poliovirus Receptor.
Notes: Clone name is SKII.4.
Rat Hybridoma producing Monoclonal Antibodies against Mouse PDCA1
— Target: Antibodies recognize a small leukocyte population of cells called intereron producing cells or plasmacyt-oid dendritic cells.
Notes: Clone names 129c1 and 927
Antibodies were produced by immunizing Wistar/CRL rats with CpG oligodeoxynucleotide 1826 or heat-killed Mycobacteria tuberculosis. The antibodies are specific for mouse IFN-producing cells (IPC).
Publication: Bone Marrow Stromal Cell Antigen 2 Is a Specific Marker of Type I IFN-Producing Cells in …
Coupled Visualization and Ablation of Specific Cells and Tissues in Zebrafish
— Background: Zebrafish is a standard model system in the field developmental biology and is particularly useful due to its extensive regenerative capabilities. The system has been used to study development by removal of cells by physical surgery and laser-mediated ablation; however these are labor in…
Novel Murine Astroviruses
— Background: Mice are critical animal models for scientists investigating both basic and applied research principles. Several novel murine astroviruses have been identified in mouse facility at Washington University School of Medicine. Astroviruses are RNA viruses often associated with gastrointestin…
Multifunctional chemical agents for metal chelation, positron emission tomography (PET) imaging, fluorescence imaging, and amyloid plaque clearance in Alzheimer’s disease
— Alzheimer’s disease (AD) is characterized by the deposition of amyloid plaques containing the amyloid beta (Aβ) peptide. Currently, no treatment is available for AD. Metal ion interactions of the Aβ peptide are believed to help formation of toxic aggregates. Developing chemical compo…
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