Murine Hybridoma producing IgG1 Monoclonal Antibody to Human B7-H3
— Target: Cluster of Differentiation, a.k.a. Neural Cell Adhesion Molecule.
Notes: Clone name is DCN.70.
Simple, stable plasmonic biosensors for point-of-care diagnosis of cardiac arrest and other conditions
— Technology Description
An interdisciplinary team of researchers at Washington University have developed a sensitive, shelf-stable, label-free system for quickly quantifying biomarkers in point-of-care settings (e.g., office, ambulance or battlefield). Localized surface plasmon resonance (LSPR) off…
Drugs to supplement microglial metabolism during treatment of Alzheimer’s disease
— Background: Alzheimer’s disease (AD) is the 6th leading cause of death in the United States, and yet causation of the disease is poorly understood and targets for therapeutic intervention are still being identified. Recently, mutations in the immune receptor TREM2 have been found to be strongl…
Treatment for Age-Related Macular Degeneration (AMD) by Targeting Cholesterol Transport in Macrophages
— Technology Description
Researchers in Prof. Rajendra Apte’s laboratory developed novel methods for treating macular degeneration and other eye diseases by targeting a cholesterol transport pathway involved in the formation of new blood vessels. Age-related macular degeneration (AMD) is a lea…
Tumor treatment for patients with neurofibromatosis type 1 (NF1)
— Technology Description
Scientists at the Washington University Neurofibromatosis Center have developed a patented, first-in-class method for treating neurofibromatosis type 1 (NF1) with small molecule inhibitors of targets in the mTOR (mammalian target of rapamycin) signaling pathway. NF1 is a rel…
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