by | Nov 7, 2019 | Colonna, Marco
— Target: CD155 is a adhesion receptor, orginally known as the cellular receptor for Polio Virus.
Notes: Clone name is SK II 4.3
Information on antibody against poliovirus receptor (CD155)
Herein, we describe the generation of a murine antibody that recognizes poliovirus receptor (CD155). We made this antibody by immunizing mice with SK-N-S1 human neuroblastoma cells. We then validated this antibody using flow cytometry.
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by | Nov 6, 2019 | Colonna, Marco
— Target: CD96 is a T cell-specific receptor indicative of T cell activation.
Notes: Clone name NK92.39.1. For use in flow cytometry.
Researchers generated the antibodies by immunizing mice with NK92 cells and selected hybridomas that plocked binding of PVR to NK92. These antibodies have been used to study natural killer cell target cell adhesion.
Publication: Cutting Edge: CD96 (Tactile) Promotes NK Cell-Target Cell Adhesion by …
by | Nov 6, 2019 | Allen, Paul
— Target: Full length mouse Vb 8.3 TCR but not 8.1 or 8.2. Vb 8.3.
Application: Flow cytometry
This antibody was made by immunizing Armenian hamsters. It was used to study the mechanisms that act to keep only one functional TCR beta-chain per cell and the effect of selecting ligand density on positive selection and endogenous receptor usage in mice.
Publication: TCR transgenic mice in which …
by | Oct 31, 2019 | Colonna, Marco
— Target: NKp44 is a novel triggering surface molecular specifcially expressed by activated natural killer cells.
Notes: Clone name 448.189 Marco Colonna, MD
Inventors generated NKp44 monocolonal antibodies by immunizing mice with a NKp44-human crystallizable fragment (Fc) fusion protein. The antibodies have been used to study innate and adaptive immune responses.
Publication: Paradoxic inhibition of human natural interferon-producing cells by the activ…
by | Oct 22, 2019 | Colonna, Marco
— Target: Cluster of Differentiation 155 protein, a.k.a. Poliovirus Receptor.
Notes: Clone name is SKII.4.
