— BOOM TCRtg mice express a T cell receptor specific for the Bt4295(541-554) epitope of the commensal bacteria Bacteroids thetaiodaomicron. This is the first mouse TCRtg line developed specific for B. theta.
— Target: Full length mouse Vb 8.3 TCR but not 8.1 or 8.2. Vb 8.3.
Application: Flow cytometry
This antibody was made by immunizing Armenian hamsters. It was used to study the mechanisms that act to keep only one functional TCR beta-chain per cell and the effect of selecting ligand density on positive selection and endogenous receptor usage in mice.
Publication: TCR transgenic mice in which …