scFv-TR3: TRAIL trimers targeted to mesothelin

— WUSTL Technology 016481

Technology Description

Researchers at Washington University in St. Louis have developed an additional targeting strategy to provide more flexibility and improve the bioactivity of the anticancer therapeutic TR3. This strategy targets TR3 to mesothelin, a tumor biomarker fr…

Mouse Hybridoma producing IgG3 Antibodies against Human TIGIT (WUCAM)

— Target: T Cell Immunoreceptor with Ig and ITIM domains, a.k.a. WUCAM

Notes: Clone available is 4E1.2. Used in flow cytometry and functional studies.

Mouse IgG3 was generated by immunizing BALB/c mice with WUCAMFLAG-Baf3 cells. This can be used to study T cell-dependent antibody responses.

Publication: A novel molecular interaction for the adhesion of follicular CD4 T cells to follicular DC

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