by | Dec 1, 2019 | Hawkins, William, Spitzer, Dirk
— WUSTL Technology 016481
Technology Description
Researchers at Washington University in St. Louis have developed an additional targeting strategy to provide more flexibility and improve the bioactivity of the anticancer therapeutic TR3. This strategy targets TR3 to mesothelin, a tumor biomarker fr…
by | Nov 27, 2019 | Boles, Kent, Colonna, Marco
— Target: T Cell Immunoreceptor with Ig and ITIM domains, a.k.a. WUCAM
Notes: Clone available is 4E1.2. Used in flow cytometry and functional studies.
Mouse IgG3 was generated by immunizing BALB/c mice with WUCAMFLAG-Baf3 cells. This can be used to study T cell-dependent antibody responses.
Publication: A novel molecular interaction for the adhesion of follicular CD4 T cells to follicular DC
by | Nov 27, 2019 | Luke, Clifford, Pak, Stephen, Silverman, Gary, Thomas, Brian
— Plasmids were generated with the NHX-2 promoter, to restrict gene expression to the C. elegans intestinal cells, driving C. elegans genes or targeting peptides, known to target different subcellular organelles, fused to a C. elegans optimized mOrange2 fluorescent protein (CemOrange2). These expressi…
by | Nov 27, 2019 | Ellebedy, Ali
— These are recombinant human monoclonal antibodies that are directed against two conserved internal proteins of the influenza virus.
by | Nov 27, 2019 | Luke, Clifford, Pak, Stephen, Silverman, Gary, Thomas, Brian
— Plasmids were generated with the NHX-2 promoter, to restrict gene expression to the C. elegans intestinal cells, driving C. elegans genes or targeting peptides, known to target different subcellular organelles, fused to a C. elegans optimized mOrange2 fluorescent protein (CemOrange2). These expressi…