Irg1 point mutant mice

by | Feb 14, 2020 | Diamond, Michael, Nair, Sharmila

— Description: CRISPR-Cas9 gene edited mice with point mutation in Irg1 (ACOD1).

Note: Please contact for additional information.

Chikungunya Monoclonal Antibodies

by | Feb 14, 2020 | Diamond, Michael, Fremont, Daved

— Description: Monoclonal antibodies that react with and/or neutralize Chikungunya virus

Publication:

Novel Monoclonal Antibodies against Dengue Viruses (1,2,3, & 4) E Proteins

by | Feb 10, 2020 | Brien, James, Diamond, Michael, Shrestha, Bimmi, Sukupolvi, Soila

— Description: Monoclonal antibodies against Dengue virus E proteins. These mAbs are generated in mouse against different Dengue viruses and have been shown, by functional assays, to neutralize infection of the individual Dengue serotypes.

Target: Dengue Virus

Notes: Contact for more info.

Publicat…

Kinase toolkit for the production of phosphorylated proteins

by | Feb 7, 2020 | Gale, Emily, Naegle, Kristen, Schaberg, Katherine, Sloutsky, Roman, Stoka, Kellie

— Background: Abnormal phosphorylation of proteins is associated with a number of human diseases including cancer, neurodegenerative disorders, and diabetes. Due to their role as phosphorlyators, kinases are popular drug targets. However, the difficulty of selectively phosphorylating a desired substra…

Lactobacillus reuteri deltaArat

by | Jan 31, 2020 | Caparon, Michael, Cervantes-Barragan, Luisa, Colonna, Marco, Di Luccia, Blanda

— Bacteria modified from the parental strain Lactobacillus reuteri 100-23 that doesn’t express the enzyme aryl aminotransferase. Culture supernatants from this bacterial strain failed to stimulate AhR reporter cells.

Publication: Lactobacillus reuteri induces gut intraepithelial CD4+CD8α&al…