— Background: Abnormal phosphorylation of proteins is associated with a number of human diseases including cancer, neurodegenerative disorders, and diabetes. Due to their role as phosphorlyators, kinases are popular drug targets. However, the difficulty of selectively phosphorylating a desired substra…
— Bacteria modified from the parental strain Lactobacillus reuteri 100-23 that doesn’t express the enzyme aryl aminotransferase. Culture supernatants from this bacterial strain failed to stimulate AhR reporter cells.
Publication: Lactobacillus reuteri induces gut intraepithelial CD4+CD8α&al…
— Murine anti-Powassan virus antibodies and hybridoma cell
Publication: An mRNA Vaccine Protects Mice against Multiple Tick-Transmitted Flavivirus Infections
— Mouse fibroblasts are isolated from Irf3-/-xlrf5-/-xlrf7-/-TKO mice. Researchers generated the mouse strains from an inbred C57BL/6 background.
Associated Publication: IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling
— Researchers developed these knock-in mice by using homologous recombination to clone the R120G mutation into exon 3 of the αB-crystallin gene (cryab). αB-crystallin (cryAB) helps to maintain protein stability in the eye lens, which is necessary for transparency. The R120G mutation causes…
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